Per caplet Co-amoxiclav: Amoxicillin trihydrate 500 mg, K clavulanate 125 mg. Per 5 mL syr Co-amoxiclav: Amoxicillin trihydrate 125 mg, K clavulanate 31.25 mg. Per 5 mL Forte syr Co-amoxiclav: Amoxicillin trihydrate 250 mg, K clavulanate 62.5 mg. Per 1 g vial Co-amoxiclav: Amoxicillin 1,000 mg, K clavulanate 200 mg
CapletAdult & childn >12 yr Severe infections: 1 caplet. Dry syrChildn 25 mg/kg 8 hrly, 1-6 yr 5 mL, <1 yr 2 mL. Forte syrChildn >6 yr 5 mL. Doses to be taken 3 times daily. InjAdult & childn >12 yr 1 g 6-8 hrly, 3 mth-12 yr 25 mg/kg 6-8 hrly, 0-3 mth 25 mg/kg 8-12 hrly. Renal dysfunction w/ CrCl 10-30 mL/min 1 g inj followed by 0.5 g IV 12 hrly. CrCl <10 mL/min 1 g inj followed by 0.5 g 24 hrly. Surgical prophylaxisAdult 1 vial at induction of anesth then up to 3-4 doses of 1 g in 24 hr.
Administration
May be taken with or without food: Best taken at the start of meals for better absorption & to reduce GI discomfort.
Contraindications
Hypersensitivity.
Special Precautions
Superinfection. Severe hepatic impairment. Pregnancy & lactation.
J01CR02 - amoxicillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.
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